CHILDHOOD CANCER REPOSITORY

Powered by

Alex's Lemonade Stand Foundation

Other Cancers


PDXs, ending in an “x”, are patient direct and have never been in vitro. Xenografts ending in “m” are established from a cell line.

The defination for the abbreviation are given below the table. Please scroll all the way down.

Please click at the top logo to return to home page.

RequestPDXPhase of DiseaseSample Type ReceivedDiagnosisCell line pO2   
     2% O25% O220%O2
COG-LL-317xPDbone marrowT-cell Acute Lymphoblastic Leukemia (ALL) -
COG-LL-319xDxperipheral bloodPre-B Acute Lymphoblastic Leukemia (ALL) -
COG-LL-329xDxbone marrowT-cell Acute Lymphoblastic Leukemia (ALL) -
COG-E-670xDxtumorEwing's Sarcoma---
COG-H-630xDxtumor (liver)Hepatoblastoma---
COG-LL-330x bone marrowAcute Lymphoblastic Leukemia (ALL)---
COG-LL-332xPDbone marrowT-cell Acute Lymphoblastic Leukemia (ALL) -
COG-LL-339x bone marrrowAcute Lymphoblastic Leukemia (ALL) - - -
COG-LL-343x  Pre-B Acute Lymphoblastic Leukemia (ALL) - - -
COG-LL-350xDxperipheral bloodPre-B Acute Lymphoblastic Leukemia (ALL) - - -
COG-LL-351x bone marrowAcute Lymphoblastic Leukemia (ALL) - - -
COG-LL-355xDxbone marrowPre-B Acute Lymphoblastic Leukemia (ALL) -
COG-LL-375x bone marrowAcute Lymphoblastic Leukemia (ALL) - - -
COG-LL-377x bone marrowAcute Lymphoblastic Leukemia (ALL) - - -
COG-LL-380x  Acute Lymphoblastic Leukemia (ALL) - - -
COG-LL-394xPDbone marrowAcute Lymphoblastic Leukemia (ALL) -
COG-LL-402xDxbone marrowPre-B Acute Lymphoblastic Leukemia (ALL) - -
COG-LL-413x bone marrowPre-B Acute Lymphoblastic Leukemia (ALL) - - -
COG-LL-436xDxbone marrowAcute Lymphoblastic Leukemia (ALL) - - -
COG-LL-456xDxbone marrow  - - -
COG-LL-489xDxperipheral blood (1st draw)T-cell Leukemia - - -
COG-LL-492xDxbone marrowT-cell Leukemia - - -
COG-LL-494xDxperipheral blood (2nd draw)T-cell Leukemia - - -
COG-LL-525xDxbone marrow (right draw)Leukemia - -
COG-LL-528xDxbone marrowLeukemia - -
COG-LY-457xPD-PMbone marrow (autopsy)Burkitt's Lymphoma
COG-LY-458xPD-PMblood (central vein) (autopsy)Burkitt's Lymphoma
COG-LY-465xPD-PMblood (left subclavian) (autopsy)Burkitt's Lymphoma
COG-LY-465xPD-PMtumor/tumorBurkitt's Lymphoma
COG-R-438xPDtumorRhabdomyosarcoma---
COG-R-668xDxtumorRhabdomyosarcoma---
COG-RB-673xPD-PMpost mortem bloodRetinoblastoma--
COG-N-410x tumorWilms' Tumor---
COG-W-477xPD-PMtumor (autopsy)Wilms' tumor---
COG-W-661xDxtumorWilms' Tumor---

1 - Phase of therapy for the patient at the time the specimen used to derive the cell line was obtained
Dx (Diagnosis): cell lines derived from samples of patients prior to treatment
PD (Progressive Disease): cell lines derived from samples of patients who relapsed after chemotherapy
PD-BMT: cell lines derived from samples of patients who relapsed after chemotherapy and bone marrow transplantation
PD-PM: cell lines derived from samples of post-mortem patients who relapsed after chemotherapy

✓ = Available/available upon request

SQ- subcutaneous injection

TV- intravenous (tail vein)

EST- ever shorter telomeres, i.e. telomerase and ALT negative

TERT+- telomerase positive

ALT - alternate lengthening of telomeres, C-circle positive