CHILDHOOD CANCER REPOSITORY

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Alex's Lemonade Stand Foundation

Brain

RequestCell Line NamePDXPhase of TherapyAge (years)Sample Type ReceivedDiagnosisAvailable Oxygen Conditions
       2% O25% O220%O2
CHLA-198-Dx tumorAnaplastic Astrocytoma--
CHLA-259-Dx14posterior fossaAnaplastic Medulloblastoma--
BT-12-Dx0.2tumorAtypical Teratoid Rhabdoid Tumor--
CHLA-135-Dx tumorAtypical Teratoid Rhabdoid Tumor--
CHLA-266-Dx1.5tumorAtypical Teratoid Rhabdoid Tumor--
COG-AR-359-Dx tumorAtypical Teratoid Rhabdoid Tumor-
COG-AR-397hnb-PD cerebrospinal fluidAtypical Teratoid Rhabdoid Tumor-
CHLA-148-Dx bone marrowDysembryoplastic Neuroepithelial Tumor--
SJ-GBM2-PD tumorGlioblastoma Multiforme--
CHLA-200-PD-PM12tumorGlioblastoma Multiforme--
COG-EP-383-- tumorEpendymoma-✓*

1 - Phase of therapy for the patient at the time the specimen used to derive the cell line was obtained
Dx (Diagnosis): cell lines derived from samples of patients prior to treatment
PD (Progressive Disease): cell lines derived from samples of patients who relapsed after chemotherapy
PD-BMT: cell lines derived from samples of patients who relapsed after chemotherapy and bone marrow transplantation
PD-PM: cell lines derived from samples of post-mortem patients who relapsed after chemotherapy

✓ = Available/available upon request

SQ- subcutaneous injection

TV- intravenous (tail vein)

EST- ever shorter telomeres, i.e. telomerase and ALT negative

TERT+- telomerase positive

ALT - alternate lengthening of telomeres, C-circle positive